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FCRLA Antikörper

Dieser Anti-FCRLA Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von FCRLA in WB und ELISA. Geeignet für Human.
Produktnummer ABIN2459358

Kurzübersicht für FCRLA Antikörper (ABIN2459358)

Target

Alle FCRLA Antikörper anzeigen
FCRLA (Fc Receptor-Like A (FCRLA))

Reaktivität

  • 11
  • 2
Human

Wirt

  • 7
  • 4
  • 2
Kaninchen

Klonalität

  • 13
Polyklonal

Konjugat

  • 13
Dieser FCRLA Antikörper ist unkonjugiert

Applikation

  • 13
  • 3
  • 1
Western Blotting (WB), ELISA
  • Aufreinigung

    Antibody is purified by peptide affinity chromatography method.

    Immunogen

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FCRLA.
  • Applikationshinweise

    FCRLA antibody can be used for detection of FCRLA by ELISA at 1:62500. FCRLA antibody can be used for detection of FCRLA by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    Konzentration

    1 mg/mL

    Buffer

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    Handhabung

    As with any antibody avoid repeat freeze-thaw cycles.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store FCRLA antibody at -20 °C.
  • Target

    FCRLA (Fc Receptor-Like A (FCRLA))

    Andere Bezeichnung

    FCRLA

    Hintergrund

    Receptors for the Fc fragment of IgG, or FCGRs, are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. FCRLA may be implicated in B-cell differentiation and lymphomagenesis.Receptors for the Fc fragment of IgG, or FCGRs (see MIM 146790), are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. All FCGR genes map to human chromosome 1. Additional genes in this region, including FREB, encode FCGR homologs that are selectively expressed in B cells and may be implicated in B-cell development and lymphomagenesis.

    Molekulargewicht

    41 kDa

    Gen-ID

    84824

    NCBI Accession

    NP_116127

    UniProt

    Q7L513
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